In an era of information overload, a paper's visual appeal often determines whether it gets read. We collaborated with a clinical research group to create a high-impact Graphical Abstract for their multi-center randomized control trial (RCT).

1. The Design Brief

The study compared the efficacy of two diverse chemotherapy regimens. The authors needed a visual summary that:

  • Could be understood in under 10 seconds.
  • Accurately represented the patient flow (CONSORT diagram).
  • Highlighted the primary endpoint (survival rates) without oversimplification.
  • Met the strict color and dimension guidelines of The New England Journal of Medicine (NEJM).

2. The Creative Process

Conceptualization & Wireframing

Our scientific illustrators met with the lead author to identify the three core messages. We drafted low-fidelity wireframes to establish the layout: Population → Intervention → Outcome.

Vector Illustration

Using Adobe Illustrator, we created custom icons to represent the patient demographics, moving away from generic clip art. We used a color-blind-friendly palette (Blue/Orange contrast) to distinguish between the Control and Treatment groups effectively.

Data Analytics Visualization

Data Visualization

We converted the raw survival data into a simplified Kaplan-Meier curve, highlighting the significant separation at month 12. Key p-values and Hazard Ratios were annotated clearly, ensuring the statistical rigor was visible at a glance.

3. Impact & Metrics

The graphical abstract was selected for the journal's online homepage feature. On social media:

  • Twitter/X: The visual post garnered 350% more impressions than text-only posts.
  • Readership: The article remained in the "Most Read" list for 3 consecutive weeks.
  • Accessibility: The design passed all accessibility checks for screen readers and color vision deficiencies.

Deliverables

We provided the client with production-ready files in TIFF (300dpi for print), EPS (vector for scaling), and a lightweight PNG for social media sharing.